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    InterSystems FHIR Server

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    Deployed on AWS
    InterSystems is launching a fully managed, enterprise-grade FHIR® service, hosted on AWS and available in the US. InterSystems will securely manage protected health data (PHI) on AWS, making it easy to develop innovative healthcare applications using FHIR.
    4.6

    Overview

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    The InterSystems FHIR® Server provides high-performance FHIR storage, searching, and analytics capabilities for healthcare applications. Whether you're creating clinical patient apps with SMART on FHIR, or developing backend services handling bulk data, you can bring them to market faster using the InterSystems FHIR Server, with absolute confidence in the availability, speed, and reliability of your data store. Evolving market needs have created new opportunities for innovation in healthcare sectors globally. Patient access and engagement, clinical decision support, social determinants of health, population health and research have all benefitted from FHIR and are being used daily to drive better outcomes. Regulatory incentives have provided greater API support and development frameworks to integrate with major health data producers, such as EHRs, QHINs, and health applications. The InterSystems FHIR Server provides the data and integration capabilities needed to connect directly to these providers, build cutting-edge solutions, and start innovating within minutes.

    Highlights

    • Easy-to-deploy production-grade FHIR servers available in minutes with built-in support for STU3, R4, and R5 versions, national core implementations (US, UK, FR, IL, AU, etc.), Da Vinci, CARIN BB, CareConnect, and many more. Includes extensive SMART on FHIR capabilities, OAuth 2.0 integration (Auth0, Google Identity, Okta, Ping, Azure AD), and SMART scope validation for use in clinical apps, payer platforms, and digital health solutions.
    • Advanced search and Bulk FHIR Exchange to rapidly import and query data from external FHIR Servers, EHRs, and healthcare platforms. Provides built-in resource operations, fast and comprehensive search APIs, and referential integrity checks to ensure scalable ingestion and querying of high-quality clinical data.
    • Integrated Analytics and the FHIR SQL Builder enable real-time intelligence, cohort building, and population health dashboards using industry standard tools, without any data duplication. Securely query your FHIR Server over xDBC with PowerBI, Tableau, or client applications.

    Details

    Delivery method

    Deployed on AWS
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    Financing for AWS Marketplace purchases

    AWS Marketplace now accepts line of credit payments through the PNC Vendor Finance program. This program is available to select AWS customers in the US, excluding NV, NC, ND, TN, & VT.
    Financing for AWS Marketplace purchases

    Pricing

    InterSystems FHIR Server

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    Pricing is based on actual usage, with charges varying according to how much you consume. Subscriptions have no end date and may be canceled any time.
    Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator  to estimate your infrastructure costs.

    Usage costs (3)

     Info
    Dimension
    Cost/unit
    vCPU deployed per hour
    $0.208
    Allocated storage per hour in 10 GB chunks
    $0.005
    If advanced features enabled (e.g., FHIR SQL Builder), 1 unit per hour
    $0.00

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    Usage information

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    Delivery details

    Software as a Service (SaaS)

    SaaS delivers cloud-based software applications directly to customers over the internet. You can access these applications through a subscription model. You will pay recurring monthly usage fees through your AWS bill, while AWS handles deployment and infrastructure management, ensuring scalability, reliability, and seamless integration with other AWS services.

    Support

    Vendor support

    InterSystems provides a fast path to get acquainted with our technology, development resources and support. Our Developer Community lets you engage to ask questions and share approaches and solutions. We offer comprehensive online learning courses. Organizations can find the full InterSystems IRIS documentation online, and when you need to solve unexpected issues, the Worldwide Response Center (WRC) is staffed 7/24/365 with professional engineers skilled in application development support@intersystems.com 

    AWS infrastructure support

    AWS Support is a one-on-one, fast-response support channel that is staffed 24x7x365 with experienced and technical support engineers. The service helps customers of all sizes and technical abilities to successfully utilize the products and features provided by Amazon Web Services.

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    Customer reviews

    Ratings and reviews

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    4.6
    68 ratings
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    68 external reviews
    External reviews are from G2 .
    Benjamin Z.

    Robust and High-Performance ERP Platform

    Reviewed on Feb 01, 2026
    Review provided by G2
    What do you like best about the product?
    I like that InterSystems IRIS is particularly well-suited for ERP applications requiring reliability, performance, and data consistency. The platform's flexibility facilitates integrations, especially with nginx as a web server and HAProxy as a reverse proxy. Additionally, the initial setup is easy, and the product's security hardening is facilitated by the online documentation.
    What do you dislike about the product?
    The areas for improvement mainly involve integrations with other platforms.
    What problems is the product solving and how is that benefiting you?
    We use InterSystems IRIS to manage complex transactional data, develop robust business logic, and expose high-performance APIs, while being well-suited for ERP applications requiring reliability, performance, and data consistency.
    Stav B.

    Essential Platform with Stellar Support, Steep Learning Curve

    Reviewed on Jan 29, 2026
    Review provided by G2
    What do you like best about the product?
    I really appreciate the Worldwide Response Center (WRC) provided by InterSystems IRIS. Their support team is incredibly responsive and knowledgeable, answering every question with great expertise. It feels like having an extension of our own team. The WRC is a game changer, especially in sectors like finance and automotive where downtime isn't an option. I value that we can set the priority of the ticket and, in crisis situations, they provide immediate access to engineers who truly solve the problem.
    What do you dislike about the product?
    The learning curve can be steep, especially for newer features or complex cloud configurations. While the documentation is extensive, it can sometimes be difficult to find specific examples for advanced scenarios.
    What problems is the product solving and how is that benefiting you?
    InterSystems IRIS provides high performance and stability, ensuring data consistency and speed for real-time transaction processing. It eliminates downtime, making our ERP robust and responsive.
    Nadyan P.

    IRIS: An Outstanding All-in-One Toolbox

    Reviewed on Jan 15, 2026
    Review provided by G2
    What do you like best about the product?
    InterSystems products, in general, are outstanding, but IRIS has something extra. What I like most is that IRIS feels like a toolbox that brings together the main InterSystems products, such as Caché and Ensemble, all in one place.
    What do you dislike about the product?
    Overall, the system is great. The only downside I’ve noticed, as a software developer, is the lack of online tutorials and discussions that cover the development process.
    What problems is the product solving and how is that benefiting you?
    As a developer, I mostly implement solutions in the healthcare area. This field involves all kinds of information, such as patient records, payments, and health tests. The volume of data is huge, and IRIS can handle all of it smoothly.
    Willyam M.

    Easy AI integration into IRIS and constant updates that evolve the platform

    Reviewed on Jan 14, 2026
    Review provided by G2
    What do you like best about the product?
    The easy integration of AI into IRIS greatly facilitates daily work. Another important point is the recurring updates released on the platform, which help keep everything constantly evolving.
    What do you dislike about the product?
    The learning process is a bit time-consuming and it may take some time until I feel completely comfortable with the use.
    What problems is the product solving and how is that benefiting you?
    I face various problems related to AI, and due to the ease of using it within the code, it assists me in my day-to-day work. Additionally, the extremely high-performing database also helps me meet my clients' needs.
    Daniel s.

    Unified Programming and Complete Documentation Facilitate Use

    Reviewed on Jan 08, 2026
    Review provided by G2
    What do you like best about the product?
    I find it very useful because of the way it is programmed and the way SQL connections are made, as everything is integrated. The global variables part is also very good, and the documentation is quite complete, making it easy to find what I need.
    What do you dislike about the product?
    I'm not a big fan of the screen creation part, as I find the ZEN framework a bit complicated to use. Additionally, I miss native resources aimed at Brazil. Another point is that the community is mostly American or European, which makes it even more difficult for those seeking support or specific content for our country.
    What problems is the product solving and how is that benefiting you?
    The quick creation of tables makes everything much easier, and the ability to create components is also a great differentiator.
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